Mucormycosis: A Lethal Phenomenon in COVID-19 Patients: A Review of Diagnostic and Therapeutic Approaches

Authors

  • Abastabar, Mahdi Associate Professor, Department of Medical Mycology, Invasive Fungi Research Center, Mazandaran University of Medical Sciences, Sari, Iran
  • Ashrafi Khozani, Mahtab PhD Student in Medical Mycology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  • Haghani, Iman Assistant Professor, Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran
  • Hedayati, Mohammad Taghi Professor, Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.Professor, Department of Medical Mycology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  • Kermani, Firoozeh PhD in Medical Mycology, Department of Medical Mycology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
  • Shokohi, Tahereh Professor, Invasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.Professor, Department of Medical Mycology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Abstract:

Coronavirus disease 2019 (COVID-19) has seriously spread worldwide. One of the problems of COVID-19 patients is co-infection with other microbial infections such as fungal infections that are severely life-threatening. Mucormycosis, one of these opportunistic fungal diseases that is mistakenly known as black fungal disease, has been reported in Iran and the world. This non-systematic review is intended to review the latest studies in the world and Iran about the incidence of mucormycosis in COVID-19 patients to better understand the disease and its predisposing factors. In general, patients with COVID-19 with underlying diseases, diabetic patients, those treated with immunosuppressive drugs, ICU patients, and patients under invasive mechanical ventilation are at higher risk for mucormycosis. Therefore, early diagnosis, treatment, and prevention methods can be effective in reducing the risk of mucormycosis in COVID-19 patients.  

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Journal title

volume 31  issue 205

pages  115- 132

publication date 2022-02

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